![]() Vitamin K 1 is synthesized from chorismate, a compound produced from shikimate via the shikimate pathway. The biosynthesis of vitamin K1 via the transformation of chorismate occurs in nine steps. Phytomenadione is often also called phylloquinone, vitamin K, or phytonadione.Ī stereoisomer of phylloquinone is called vitamin k 1 (note the difference in capitalization). In 1943 Edward Doisy and Henrik Dam were given a Nobel Prize for its discovery. Phytomenadione was first isolated in 1939. Found sources include green vegetables, vegetable oil, and some fruit. It works by supplying a required component for making a number of blood clotting factors. Use during pregnancy is considered safe, use is also likely okay during breastfeeding. Severe allergic reactions may occur when it is injected into a vein or muscle, but this has mainly happened when large doses of a certain type of supplement containing castor oil were given intravenously. Side effects when given by injection may include pain at the site of injection. It is considered a safe treatment and saves many children from death and severe neurologic deficit every year. Many countries in the world choose intramuscular injections in newborn to keep them safe from severe bleeding (VKDB). When given by injection benefits are seen within two hours. Use is typically recommended by mouth, intramuscular injection or injection under the skin. ![]() It is also recommended to prevent and treat vitamin K deficiency bleeding in infants. This includes warfarin overdose, vitamin K deficiency, and obstructive jaundice. ![]() Īs a supplement it is used to treat certain bleeding disorders. It is on the World Health Organization's List of Essential Medicines. Phytomenadione, also known as vitamin K 1 or phylloquinone, is a vitamin found in food and used as a dietary supplement.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |